Author

Antonio Jacobo Lopez

University of California, DavisORCID 0000-0003-2391-3593Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Ala MoshiriiD· 2 shared A. ThompsoniD· 1 shared Addy ThamiD· 1 shared Alejandra Quiroz AlonsoiD· 1 shared Andrea MinellaiD· 1 shared Andrew John LoteryiD· 1 shared Andy ShaoiD· 1 shared Bin GuaniD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Ala MoshiriORCID

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2 papers

Recent·Most cited

Developmental BiologyInvestigative Ophthalmology & Visual SciencePeer-reviewedNov 3, 2022

Zfp503/Nlz2 is Required for RPE Differentiation and Optic Fissure Closure

Elangovan Boobalan, A. Thompson, Ramakrishna P. Alur…·Brian P. Brooks

The paper shows that Zfp503 is essential for RPE differentiation and optic fissure closure, with loss of function leading to uveal coloboma and altered gene expression in developing mouse eyes.

11 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintAug 9, 2021

Arap1 Loss Causes RPE Phagocytic Dysfunction and Subsequent Photoreceptor Death

Andy Shao, Antonio Jacobo Lopez, JiaJia Chen…·Ala Moshiri

This study shows that Arap1 in retinal pigment epithelium (RPE) is essential for photoreceptor survival through its role in phagocytosis, as Arap1 deficiency leads to photoreceptor degeneration.

DOI 10.1101/2021.08.09.455745

mouseexperimental assay

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