Author

James D. Byrne

University of IowaORCID 0000-0002-6436-2866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:rat· 1

Frequent Co-Authors

Emily Witt· 2 shared Alicia T. CotoiaiD· 1 shared Arielle B. Cafi· 1 shared Brett A. Wagner· 1 shared Colin J. Reis· 1 shared Erin J. Elizalde· 1 shared Fan ShuiD· 1 shared Giovanni TraversoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

Emily Witt

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Enhancing HIPEC for Ovarian Cancer using Adjunctive Biomaterials

Jianling Bi, Emily Witt, Arielle B. Cafi, Fan Shu, Megan McGovern, Sri Naga Swetha Tunuguntla, Kyle R. Balk, Lillian Boge, Qi Wang, Juan Du, Ian C. Sutton, Colin J. Reis, Jacob M. Spreng, Erin J. Elizalde, Uwajachukwumma A. Uzomah, , James D. Byrne

This paper introduces CO-GEMs as a multifunctional adjunct to HIPEC, improving efficacy, preventing adhesions, and reducing nephrotoxicity in ovarian cancer models.

bioRxiv · Oct 26, 2025 · PreprintBioengineering

Activation of Heme Metabolism Promotes Tissue Health after Intraarticular Injury or Surgical Exposure

Suryamin Liman, Piedad C. Gómez-Contreras, Madeline R. Hines, Emily Witt, Jacob S. Fisher, Kevin J. Lu, Lauren D. McNally, Alicia T. Cotoia, Maxwell Y. Sakyi, Brett A. Wagner, Michael Scott Tift, Jessica E. Goetz, James D. Byrne, Mitchell C. Coleman

This study shows that activating heme metabolism via carbon monoxide reduces oxidative damage and improves joint health after injury.

bioRxiv · May 29, 2024 · PreprintCell Biology