Heejung Chun

This study reviews and analyzes preclinical and clinical studies on PD-1/PD-L1 blockade in Alzheimer's disease, finding potential benefits in reducing pathology and improving cognitive function.

The paper reproduces DIANA fMRI experiments in anesthetized mice and analyzes the signal origin, suggesting PSS oscillations may generate DIANA signals rather than direct neuronal responses.

This study demonstrates that DIANA fMRI can reveal multiple neural circuits through spatiotemporal activation mapping in anesthetized mice.

This paper identifies hemoglobin as a peroxidase with therapeutic potential for oxidative stress-related diseases and presents KDS12025 as a drug candidate that enhances its activity.

The paper shows that astrocytes form more connections with engram neurons after learning, and these connections are stabilized by neuronal activity.

This study shows astrocytes regulate NMDAR tone through Best1-mediated glutamate and D-serine release, which is essential for cognitive flexibility and memory repotentiation during reversal learning.

The paper uses intravital imaging to study cellular changes after cerebral microinfarction in mice, finding that astrocyte reactivity leads to glial scar formation.