Weijie Zhang

This study identifies an early neutrophil interferon program that predicts resistance to anti-PD1 therapy and limits durable anti-tumor immunity.

This paper identifies AADAT as a metabolic immune checkpoint in TNBC that promotes immune evasion by regulating malate and CoQ10, and shows that malate supplementation can reverse immunotherapy resistance.

The paper identifies cancer driver lncRNAs by analyzing their association with cancer driver genes and topologically associated domains, revealing 256 oncogenic, 177 tumor suppressive, and 75 dual-function lncRNAs.

The paper analyzes bone metastases from six cancer types using single-cell RNA-seq to identify three immune archetypes and their mechanisms of bone colonization.

The paper uses two-photon calcium imaging to study how infrared neural stimulation affects excitatory and inhibitory neurons in mouse somatosensory cortex.

This study develops a precise photothrombosis method to investigate microvascular network dynamics and neurodegeneration effects in the cerebral cortex.

This work evaluates CRISPR lineage recorders using TraceQC to analyze mutation speed and distribution across platforms.