Hyun-Hwan Jeong

BARCS extends beta-binomial regression to handle complex CRISPR screen designs, showing improved essential gene recovery but calibration issues in gene-level summaries.

MARRVEL-MCP enables natural language variant interpretation by allowing LLMs to autonomously construct workflows using curated genomic tools, improving performance over models without tool access.

This study shows that genetic inactivation of beta-catenin improves desmoplakin cardiomyopathy by restoring oxidative phosphorylation gene expression, while its activation worsens the condition.

This paper introduces PARMESAN, a tool that predicts drug-gene relationships using PubMed data, showing high accuracy for top-scoring predictions.

This work evaluates CRISPR lineage recorders using TraceQC to analyze mutation speed and distribution across platforms.

The paper identifies CXCR6 as a host genetic factor associated with severe COVID-19 through transcriptomic analysis and shows its protective effect in lung tissue.

TraceQC provides quality control for CRISPR lineage tracing data to improve lineage tree reconstruction.

CRISPRCloud2 provides a cloud-based platform for deconvoluting CRISPR screen data with tools for read mapping, statistical analysis, visualization, and integration with other resources.

SAVE provides a cloud-based pipeline for deconvolving CRISPR pooled screening data, enabling analysis and visualization of NGS files through a secure web platform.