Author

Yunfeng Ding

Baylor College of MedicineORCID 0000-0001-6592-1159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Xiang H.-F. ZhangiD· 4 shared Charlotte Helena RivasiD· 3 shared Dane K. HoffmaniD· 3 shared Fengshuo LiuiD· 3 shared Hilda L. ChaniD· 3 shared Liqun YuiD· 3 shared Luis Becerra-DomingueziD· 3 shared Weijie ZhangiD· 3 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Xiang H.-F. ZhangORCID

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 1, 2026

Early dynamics of a neutrophil interferon program drive immunotherapy resistance and limit durable anti-tumor immunity

Yang Gao, Emmanuel Anning, Linhua Wang…·Xiang H.-F. Zhang

This study identifies an early neutrophil interferon program that predicts resistance to anti-PD1 therapy and limits durable anti-tumor immunity.

DOI 10.64898/2026.09.30.755684

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Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJun 22, 2026

Rat somatic genome editing enables ER+ breast cancer modeling

Wen Bu, Tobie D. Lee, Meenakshi Anurag…·Yi Li

This study enables efficient somatic genome editing in rats to model ER+ breast cancer, showing that rat tumors recapitulate key features of human ER+ breast cancer not observed in mice.

DOI 10.1073/pnas.2529653123

ratexperimental assay

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Cancer BiologyCell GenomicsPeer-reviewedMay 23, 2025

Single cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization.

Fengshuo Liu, Yunfeng Ding, Zhan Xu…·Xiang H.-F. Zhang

The paper analyzes bone metastases from six cancer types using single-cell RNA-seq to identify three immune archetypes and their mechanisms of bone colonization.

32 citationstop 1%

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Cancer BiologybioRxivPreprintMay 7, 2024

Unbiased metastatic niche-labeling identifies estrogen receptor-positive macrophages as a barrier of T cell infiltration during bone colonization

Zhan Xu, Fengshuo Liu, Yunfeng Ding…·Xiang H.-F. Zhang

1 citation

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