Author

Zhonghui Xu

Brigham and Women's HospitalORCID 0000-0002-6469-9178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Edwin K. SilvermaniD· 2 shared Peter J. CastaldiiD· 2 shared Aabida SaferaliiD· 1 shared Alain LaederachiD· 1 shared Christopher VollmersiD· 1 shared Craig P. HershiD· 1 shared Dávid DeriteiiD· 1 shared Feng GuoiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Edwin K. SilvermanORCID

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2 papers

Recent·Most cited

HHIP protein interactions in lung cells provide insight into COPD pathogenesis

Dávid Deritei, Hiroyuki Inuzuka, Peter J. Castaldi, Jeong Hyun Yun, Zhonghui Xu, Wardatul Jannat Anamika, John M. Asara, Feng Guo, Xiaobo Zhou, Kimberly Glass, Wenyi Wei, Edwin K. Silverman

The paper identifies HHIP protein interactions in lung cells, revealing new connections to COPD GWAS genes and providing insights into COPD pathogenesis.

Human Molecular Genetics · Feb 10, 2025Peer-reviewedGenetics

Characterization of a Disease-Associated NPNT Functional Splicing Genetic Variant in Human Lung Tissue via Long-Read Sequencing

Aabida Saferali, Zhonghui Xu, Gloria Sheynkman, Craig P. Hersh, Michael H. Cho, Edwin K. Silverman, Alain Laederach, Christopher Vollmers, Peter J. Castaldi

The paper identifies a genetic variant in NPNT associated with COPD risk and lung function through splicing analysis using long-read sequencing.

medRxiv · Oct 20, 2020 · PreprintGenetic & Genomic Medicine