Xiaobo Zhou

The paper investigates HHIP's role in epithelial wound healing and links its dysfunction to COPD susceptibility through computational modeling and experimental validation.

This study shows that non-mutated human tau causes neurodegeneration in a microglia-dependent manner in a mouse model of Alzheimer's disease.

The paper identifies HHIP protein interactions in lung cells, revealing new connections to COPD GWAS genes and providing insights into COPD pathogenesis.

The paper identifies FBXO38 as a novel COPD susceptibility gene by analyzing genetically driven alternative splicing and finding a protective exon associated with COPD risk.

This study expands the genetic landscape of COPD by identifying 82 risk loci, revealing associations with lung function, cell types, and comorbidities.

The paper integrates existing interactome data with new experimental interactions to identify a COPD-related disease network module.