Author

Polina K. Derevyanko

Princess Máxima CenterORCID 0000-0002-6472-7378Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anita T. van Oort· 1 shared Anja Krippner‐HeidenreichiD· 1 shared Christian Michel ZwaaniD· 1 shared Constanze BoniferiD· 1 shared Josef H. VormooriD· 1 shared L. Daniel Mata Casimiro· 1 shared Laura E. SwartiD· 1 shared Luca M. van den Brink· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anita T. van Oort

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1 paper

Recent·Most cited

RUNX1::RUNX1T1 Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia

Polina K. Derevyanko, Laura E. Swart, L. Daniel Mata Casimiro, Luca M. van den Brink, Anita T. van Oort, Minoo Ashtiani, Christian Michel Zwaan, Anja Krippner‐Heidenreich, Constanze Bonifer, Raymond Michel Schiffelers, Josef H. Vormoor, Sophie G. Kellaway, Olaf T Heidenreich

This study shows that depletion of RUNX1::RUNX1T1 in AML cells reduces stemness and promotes differentiation into granulocytic and eosinophilic/mast cell-like populations.

bioRxiv · Feb 13, 2025 · PreprintCancer Biology