Author

David M. Brinkley

Massachusetts Institute of TechnologyORCID 0000-0002-6472-9330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Wen· 1 shared Ainsley Brockman· 1 shared Dapeng ZhangiD· 1 shared Desmond L. Edwards· 1 shared Jon McGinniD· 1 shared Joseph D. MougousiD· 1 shared Larry A. GallagheriD· 1 shared Minola Motha de SilvaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Wen

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2 papers

Recent·Most cited

Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system

David M. Brinkley, Savannah K Bertolli, Larry A. Gallagher, Yongjun Tan, Minola Motha de Silva, Ainsley Brockman, Dapeng Zhang, Snow Brook Peterson, Joseph D. Mougous

The paper shows that Pseudomonas bacteria use a single regulatory pathway to coordinate defense against both bacterial and viral threats across multiple species.

Cell Host & Microbe · Aug 1, 2025Peer-reviewedMicrobiology

An expanded genetic toolkit for inducible expression and targeted gene silencing in Rickettsia parkeri

Jon McGinn, A. Wen, Desmond L. Edwards, David M. Brinkley, Rebecca L. Lamason

This paper develops inducible gene expression and CRISPRi-mediated gene knockdown systems in Rickettsia parkeri to study its infectious life cycle.

Journal of Bacteriology · Jun 6, 2024Peer-reviewedMicrobiology