Larry A. Gallagher

The paper identifies an Esx secretion system in Actinomycetota that defends against parasitic Patescibacteria by sensing epibionts and triggering a transcriptional response.

The paper identifies the Rnf electron transport chain as a susceptibility determinant for Bte2 pore-forming toxins in Bacteroides, showing its role in toxin-mediated membrane depolarization during gut colonization.

The paper identifies a Pseudomonas aeruginosa bacteriophage, Clew-1, that uses Psl as a receptor to disrupt biofilms and reduce bacterial burden in a mouse model.

The paper shows that Pseudomonas bacteria use a single regulatory pathway to coordinate defense against both bacterial and viral threats across multiple species.

This paper introduces a method called 3D-seq to map DNA-protein interaction sites in vivo using a modified cytosine deaminase, demonstrating its application in Pseudomonas aeruginosa transcription factors.