Proteome-wide ubiquitinome profiling reveals substrate-specific dynamics within the USP7 network
Joyce Wolf van der Meer, Jan A. van der Knaap, Ayestha Sijm, Karel Bezstarosti, Dick H. W. Dekkers, Wouter A. S. Doff, Jeroen Demmers, C. Peter Verrijzer
This study uses proteomics to show that USP7's deubiquitylation effects are substrate-specific, revealing its role in neurodevelopment and tumor suppression.
Molecular & Cellular Proteomics · Jun 16, 2026Peer-reviewedBiochemistry