Cancer BiologyNature CommunicationsPeer-reviewed
Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity
Adrián Varela-Vázquez, Amanda Guitián‐Caamaño, Paula Carpintero-Fernández…·María D. Mayán
This study shows that Cx43 enhances the effectiveness of BRAF/MEKi by reducing DNA repair, leading to increased DNA damage and cellular senescence, and proposes a novel therapeutic approach using sEVs.
11 citations