Author

Alexandre Thomas

University of GenevaORCID 0000-0002-6500-2037Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

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Daria IvanovaiD· 1 shared Elena DoriaiD· 1 shared Patrick MeraldiiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperCell Biology

Daria IvanovaORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintMay 2, 2024

Transient lagging chromosomes cause primary microcephaly

Elena Doria, Daria Ivanova, Alexandre Thomas, Patrick Meraldi

This study shows that transient lagging chromosomes in anaphase, caused by loss of WDR62 and ASPM, lead to impaired cell proliferation and primary microcephaly through Aurora-B-dependent activation of 53BP1 and p21.

DOI 10.1101/2024.05.02.592199

humanDrosophila