This study develops a plasma protein binding model to predict unbound cortisol and cortisone concentrations by accounting for changes in ligand and protein concentrations across physiological states.

bioRxiv · Apr 17, 2026 · PreprintPharmacology & Toxicology

Proteomic Profiling of Human Omental and Subcutaneous Adipose Tissue in Individuals with a Broad Range of BMI.

Alex Zelter, Yue Winnie Wen, Michael E. Riffle, Lindsay C. Czuba, Aprajita S. Yadav, Jerry Zhu, Jessica M. Snyder, Aaron J. Maurais, Jeffrey LaFrance, Saurabh Khandelwal, Judy Y. Chen, Estell Williams, Zoe E. Parr, Daniel Y. Kim, Katya B. Rubinow, , Nina Isoherranen

This study presents a comprehensive proteomic dataset of human omental and subcutaneous adipose tissue across a wide BMI range to uncover depot-specific biological changes associated with adiposity.

Scientific Data · Mar 5, 2026Peer-reviewedSystems Biology

Development and Validation of a Novel LC-MS/MS Based Proteomics Method for Quantitation of Retinol Binding Protein 4 (RBP4) and Transthyretin (TTR)

Aprajita S. Yadav, Katya B. Rubinow, Alex Zelter, Aurora K. Authement, Bryan R. Kestenbaum, John Kenneth Amory, Nina Isoherranen

This study develops and validates an LC-MS/MS method for absolute quantitation of RBP4 and TTR in serum and plasma, showing good linearity, precision, and correlation with ELISA.

Journal of Proteome Research · Sep 10, 2025Peer-reviewedPhysiology