Abhinav Nath

Liver Fatty Acid Binding Protein (FABP1) Affects Cytochrome P450 2C9 (CYP2C9)-Mediated Metabolism in Human Liver Models

The paper shows that FABP1 affects CYP2C9-mediated drug metabolism in human liver models, improving prediction accuracy when included in physiologically based models.

Function within Disorder: Small heat shock proteins use different functional regions to chaperone tau aggregation

This study shows HSPB1 and HSPB5 use distinct N-terminal regions to delay tau aggregation, with HSPB1 under normal conditions and HSPB5 under stress.

Kinetics of cortisol and cortisone binding to corticosteroid binding globulin and albumin in vivo

This study develops a plasma protein binding model to predict unbound cortisol and cortisone concentrations by accounting for changes in ligand and protein concentrations across physiological states.

Tau4RD fibril polymorphism is imprinted during early aggregation

This study uses pulsed HDX-MS to investigate whether tau4RD fibril polymorphism is imprinted during early aggregation or arises from structural rearrangements later in the process.