Yue Winnie Wen

The paper shows that FABP1 affects CYP2C9-mediated drug metabolism in human liver models, improving prediction accuracy when included in physiologically based models.

This study identifies the main cytochrome P450 enzymes responsible for metabolizing Δ8-THC in human liver microsomes and shows that CYP2C9 is the primary catalyst for its 11-hydroxylation.

This study presents a comprehensive proteomic dataset of human omental and subcutaneous adipose tissue across a wide BMI range to uncover depot-specific biological changes associated with adiposity.

This study develops a liver distribution model incorporating intracellular lipid partitioning and FABP1 binding to improve Kp prediction accuracy for drugs.