Author

Daniel C. Angst

ETH ZurichORCID 0000-0002-6512-4595Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Roland R. RegoesiD· 3 shared Sebastian BonhoefferiD· 3 shared Malte MuetteriD· 2 shared Alejandro Escalera LedermanniD· 1 shared Alex R. HalliD· 1 shared Anaëlle FaitiD· 1 shared Chujin RuaniD· 1 shared David R. JohnsoniD· 1 shared

Activity by Year

2026-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersMicrobiology

Roland R. RegoesORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Parallel evolution of full-length genomes in a long-term evolution experiment with phage ΦX174

Eva Bons, Hélène Chabas, Hannelore MacDonald, Alejandro Escalera Ledermann, Sira Ösze, Jenny Dunstan, Nicolas Ochsner, Daniel C. Angst, Sebastian Bonhoeffer, Roland R. Regoes

The paper tracks parallel evolution of full-length genomes in bacteriophage populations over 412 generations, showing non-neutral evolutionary dynamics and biases in phylodynamic analysis.

PLoS Biology · Oct 29, 2026Peer-reviewedEvolutionary Biology

Antimicrobial Combination Effects at Sub-inhibitory Doses do not Reliably Predict Effects at Inhibitory Concentrations

Malte Muetter, Daniel C. Angst, Roland R. Regoes, Sebastian Bonhoeffer

The paper evaluates how well sub-inhibitory drug combination effects predict inhibitory effects, finding that interaction labels depend on concentration and mixing ratio.

bioRxiv · Sep 1, 2026 · PreprintMicrobiology

High-Throughput Quantification of Population Dynamics using Luminescence

Malte Muetter, Daniel C. Angst, Roland R. Regoes, Sebastian Bonhoeffer

This study compares luminescence and CFU assays for quantifying bacterial population decline at super-MIC concentrations, finding they differ due to physiological effects and the quantity of interest.

eLife · Aug 5, 2026Peer-reviewedMicrobiology

Inhibition of multidrug-resistant Staphylococcus aureus by commensal bacterial species from the human nose

Anaëlle Fait, Daniel C. Angst, Valeria Stylianou, Laura Brülisauer, Silvio D. Brugger, Alex R. Hall

This study identifies nasal commensal bacterial species and combinations that inhibit MRSA, including antibiotic-resistant strains, through in vitro experiments.

bioRxiv · Mar 1, 2026 · PreprintMicrobiology

Plasmid transfer and loss probabilities interactively determine antibiotic resistance spread in surface-associated bacterial biomass

Josep Ramoneda, Deepthi P Vinod, Yinyin Ma, Chujin Ruan, Julian Schmidt, Michael Manhart, Daniel C. Angst, David R. Johnson

The paper models and experimentally tests how plasmid transfer and loss probabilities influence antibiotic resistance spread between colliding bacterial colonies.

bioRxiv · Jan 8, 2026 · PreprintMicrobiology