Author

Abraham Grant Shain

San Diego State UniversityORCID 0000-0002-6532-7915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1

Frequent Co-Authors

Abigail RiederiD· 2 shared Barbara BaileyiD· 2 shared Clarissa SavkoiD· 2 shared Faid Jaafar· 2 shared Joy A. PhillipsiD· 2 shared Mark Alan SussmaniD· 2 shared Sophie Rokaw· 2 shared Ariana Mardani· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Abigail RiederORCID

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2 papers

Recent·Most cited

Myocardial infarction injury is exacerbated by nicotine in vape aerosol exposure

Clarissa Savko, Carolina Esquer, Claudia Molinaro, Sophie Rokaw, Abraham Grant Shain, Faid Jaafar, Morgan K. Wright, Joy A. Phillips, Tyler J. Hopkins, Sama Mikhail, Abigail Rieder, Ariana Mardani, Barbara Bailey, Mark Alan Sussman

This study shows that nicotine in vape aerosol worsens myocardial infarction outcomes in mice, with no comparable effect from vape alone.

Journal of the American Heart Association · Dec 20, 2024Peer-reviewedMolecular Biology

Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females

Abraham Grant Shain, Clarissa Savko, Sophie Rokaw, Faid Jaafar, Abigail Rieder, Morgan Wright, Joy A. Phillips, Nickolas Konja, Sama Michael, Haley Mathews, Gina Jerjees, Barbara Bailey, Mark Alan Sussman

This study shows nicotine in vape aerosol induces p16 expression and collagen deposition in male cardiac tissue but not females, while vape alone increases fibroblasts without collagen changes.

bioRxiv · Aug 1, 2024 · PreprintMolecular Biology