Mark Alan Sussman

This study shows that vape aerosol exposure reduces voluntary exercise in mice, with a significant 32% decrease in female running laps compared to controls.

This study shows the PIDDosome restricts cardiomyocyte polyploidization during postnatal heart development through p21/Cdkn1a, independent of p53.

This study shows that nicotine in vape aerosol worsens myocardial infarction outcomes in mice, with no comparable effect from vape alone.

This study shows nicotine in vape aerosol induces p16 expression and collagen deposition in male cardiac tissue but not females, while vape alone increases fibroblasts without collagen changes.

This study demonstrates vaping-induced pulmonary injury in mice using a JUUL pen inhalation model, showing structural and transcriptional changes linked to respiratory distress.

The paper shows that culturing adult cardiac stem cells reduces transcriptome variability and alters gene expression, potentially affecting their therapeutic efficacy.