Author

Stefania Purgato

MRC Human Genetics UnitORCID 0000-0002-6533-8569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Adam BuckleiD· 1 shared Catherine NaughtoniD· 1 shared Claudia Rita CatacchioiD· 1 shared Covadonga HuidobroiD· 1 shared Graeme R. GrimesiD· 1 shared Mariano RocchiiD· 1 shared Nick GilbertiD· 1 shared Ryu‐Suke NozawaiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Adam BuckleORCID

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1 paper

Recent·Most cited

Human centromere formation activates transcription and opens chromatin fibre structure

Catherine Naughton, Covadonga Huidobro, Claudia Rita Catacchio, Adam Buckle, Graeme R. Grimes, Ryu‐Suke Nozawa, Stefania Purgato, Mariano Rocchi, Nick Gilbert

The paper investigates the chromatin structure changes during human centromere formation, finding that it involves active transcription and open chromatin, while surrounding regions become repressed and compact.

bioRxiv · Aug 1, 2021 · PreprintMolecular Biology