Human centromere formation activates transcription and opens chromatin fibre structure
Catherine Naughton, Covadonga Huidobro, Claudia Rita Catacchio, Adam Buckle, Graeme R. Grimes, Ryu‐Suke Nozawa, Stefania Purgato, Mariano Rocchi, Nick Gilbert
The paper investigates the chromatin structure changes during human centromere formation, finding that it involves active transcription and open chromatin, while surrounding regions become repressed and compact.
bioRxiv · Aug 1, 2021 · PreprintMolecular Biology