Molecular BiologyAntimicrobial Agents and ChemotherapyPeer-reviewed
C. albicans Zn Cluster Transcription Factors Tac1 and Znc1 are Activated by Farnesol to Up Regulate a Transcriptional Program Including the Multi-Drug Efflux Pump CDR1
Zhongle Liu, John M. Rossi, Lawrence C. Myers
The paper shows farnesol activates Tac1 and Znc1 in C. albicans, leading to upregulation of CDR1, which increases farnesol efflux and promotes growth under high farnesol conditions.
26 citations