Zhongle Liu

This study shows that Dna2 forms condensates that enhance DNA end resection in yeast, with phosphorylation regulating condensate stability and function.

The paper identifies structure-activity relationships for diarylpyrazole inhibitors of the fungal kinase Yck2, showing improved selectivity and antifungal activity.

The paper uses chemoproteomic profiling to identify selective anti-fungal kinase inhibitors targeting C. albicans CK1 homologs.

The paper shows farnesol activates Tac1 and Znc1 in C. albicans, leading to upregulation of CDR1, which increases farnesol efflux and promotes growth under high farnesol conditions.