BioengineeringNucleic Acids ResearchPeer-reviewed
Highly Specific Enrichment of Rare Nucleic Acids using Thermus Thermophilus Argonaute with Applications in Cancer Diagnostics
Jinzhao Song, Jorrit W. Hegge, Michael G. Mauk…·Haim H. Bau
The paper introduces NAVIGATER, a method using TtAgo to enrich rare nucleic acid alleles, demonstrating 60-fold enrichment of KRAS G12D in pancreatic cancer blood samples.
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