Author

Jorrit W. Hegge

Wageningen University & Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

John van der OOSTiD· 2 shared Chirlmin JooiD· 1 shared Daan C. SwartsiD· 1 shared Erica L. CarpenteriD· 1 shared Haim H. BauiD· 1 shared Jacob Edward TilliD· 1 shared Jazmine J. Mays· 1 shared Jeroen KneppersiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

John van der OOSTORCID

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2 papers

Recent·Most cited

BioengineeringNucleic Acids ResearchPeer-reviewedDec 3, 2019

Highly Specific Enrichment of Rare Nucleic Acids using Thermus Thermophilus Argonaute with Applications in Cancer Diagnostics

Jinzhao Song, Jorrit W. Hegge, Michael G. Mauk…·Haim H. Bau

The paper introduces NAVIGATER, a method using TtAgo to enrich rare nucleic acid alleles, demonstrating 60-fold enrichment of KRAS G12D in pancreatic cancer blood samples.

149 citations

humanDNA methylation

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedMay 3, 2019

DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute

Jorrit W. Hegge, Daan C. Swarts, Stanley D. Chandradoss…·John van der OOST

This study characterizes CbAgo, a mesophilic prokaryotic Argonaute that enables DNA-guided DNA cleavage at moderate temperatures using specific siDNA guides.

201 citationstop 3%

bacteria (other)DNA methylation

𝕏 PostBluesky