Perturbed fatty-acid metabolism is linked to localized chromatin hyperacetylation, increased stress-response gene expression and resistance to oxidative stress
Jarmila Princová, Clàudia Salat-Canela, Petr Daněk, Anna Marešová, Laura de Cubas, Jürg Bähler, José Ayté, Elena Hidalgo, Martin Převorovský
The paper shows that fatty-acid synthesis defects in fission yeast lead to chromatin hyperacetylation, stress-response gene activation, and oxidative stress resistance.
PLoS Genetics · Jan 10, 2023Peer-reviewedMolecular Biology