The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation
Tapan Sharma, Daniel C.L. Robinson, Hanna Witwicka, Francis Jeffrey Dilworth, Anthony N. Imbalzano
This study shows that bromodomains in BRG1 and BRM promote chromatin binding and are essential for skeletal muscle differentiation by regulating gene expression and cell cycle exit.
Nucleic Acids Research · Jul 8, 2021Peer-reviewedMolecular Biology