Tapan Sharma

This study identifies TCEAL7 as a BRG1-regulated target of calcineurin signaling that promotes myoblast differentiation and reveals its role in myogenic gene regulation.

This study shows PADs and mSWI/SNF chromatin remodelers reciprocally regulate each other's expression and function in skeletal muscle differentiation and regeneration.

This study evaluates the pro-apoptotic effects of Brazilin and its derivatives on breast cancer cell lines, showing selective induction of mitochondrial stress and cell death in triple-negative cells.

AAVone is a single-plasmid system for AAV production that increases yield, reduces DNA impurities, and simplifies the manufacturing process.

This study shows that Pkm2 and Pkm1 regulate chromatin remodeling and histone phosphorylation during myoblast differentiation by affecting mSWI/SNF subunits and histone modifications.

The paper investigates the roles of three mSWI/SNF subfamilies in myoblast differentiation, finding distinct requirements for BAF and ncBAF complexes, while PBAF is dispensable.

This study shows that bromodomains in BRG1 and BRM promote chromatin binding and are essential for skeletal muscle differentiation by regulating gene expression and cell cycle exit.

This study shows SMARCAL1 and BRG1 regulate ATM/ATR transcription, which is essential for the G2/M checkpoint response to DNA damage.