J Y Kang

This paper designs AI-driven nanobinders targeting the TSLPR-IL-7R heterodimer interface to suppress type 2 inflammatory signaling, showing that geometric mimicry of the native cytokine is more effective than affinity alone.

GDTR measures nucleotide settling depth in genomic models to reveal biological grammar stability across layers, showing splice sites settle earlier than intronic regions and identifying variant impact through differential depths.