Yoonjin Cho

The paper studies dedifferentiation in Arabidopsis thaliana using single-cell RNA sequencing, revealing cell-type-specific transcriptional changes and the role of phytohormones and chromatin remodeling.

The paper evaluates which layers of genomic foundation models are most critical for variant classification, finding that representative and load-bearing layers differ in their roles and positions within the model.

GDTR measures nucleotide settling depth in genomic models to reveal biological grammar stability across layers, showing splice sites settle earlier than intronic regions and identifying variant impact through differential depths.