Joëlle Rüegg

Germline genomic and methylomic dynamics following three generations of early-life metabolic challenges

This study examines multigenerational effects of early-life metabolic challenges on germline genome and methylation in mice, finding genomic instability and methylation changes linked to transposable elements.

Epigenetic changes induced by developmental PFAS exposure in zebrafish associate with behavioral alterations in unexposed offspring

This study shows that PFAS exposure during development causes transgenerational behavioral effects in zebrafish through epigenetic changes that persist in unexposed offspring.

Temporal structure of chemical stress controls single-cell inhibition and recovery in photosynthetic microorganisms

The paper shows that fluctuating chemical stress causes stronger initial inhibition but allows partial recovery in some cells of a microalga, revealing that stress timing affects single-cell reversibility.

A mixture of endocrine disrupting chemicals linked to lower birth weight induces adipogenesis and transcriptional changes related to birth weight alterations and diabetes

This study shows that an EDC mixture linked to lower birth weight increases adipogenesis and induces transcriptomic changes associated with birth weight and diabetes.

From Cohorts to Molecules: Adverse Impacts of Endocrine Disrupting Mixtures

The paper identifies EDC mixtures linked to adverse health outcomes and shows they disrupt gene regulatory networks in vitro and in vivo.