Jacqueline M. Bliley

The paper introduces multi-modal photoFRESH, a 3D bioprinting technique that enables precise control of crosslinking, stiffness, and biomolecular tethering through localized photochemistry, resulting in structurally complex and heterogeneous tissue constructs.

This study uses FRESH 3D bioprinting to engineer complex skeletal muscle architectures that mimic native structures and exhibit contractile functionality.

The paper shows that transient Notch activation converts human pluripotent stem cell-derived cardiomyocytes into Purkinje fiber-like cells with altered electrophysiology and gene expression.