Author

Laurence M Morel

The University of Texas at San Antonio Health Science CenterORCID 0000-0002-6622-1290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Mansour MohamadzadehiD· 2 shared Milind V. Joshi· 2 shared Seung Chul Choi· 2 shared Yong GeiD· 2 shared Ahmed Samir ElshikhaiD· 1 shared Cassandra LaPlante· 1 shared Cenxiao C. Fang· 1 shared Damian JimeneziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Mansour MohamadzadehORCID

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2 papers

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedNov 22, 2025

Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus

Seung Chul Choi, Yong Ge, Ahmed Samir Elshikha…·Laurence M Morel

This study shows that inhibiting glycolysis with 2DG reduces TFH cell expansion and autoantibody production in lupus-prone mice, with potential therapeutic implications for SLE.

16 citationstop 1%

mousehuman

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ImmunologybioRxivPreprintNov 25, 2024

Glutaminolysis promotes the function of follicular helper T cells in lupus-prone mice

Seung Chul Choi, Yong Ge, Milind V. Joshi…·Laurence M Morel

This study shows that glutaminolysis supports lupus Tfh cell function, and its inhibition reduces autoantibody production and disease in lupus-prone mice.

DOI 10.1101/2024.11.25.625088

mouseproteomics

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