Yong Ge

This study shows that inhibiting glycolysis with 2DG reduces TFH cell expansion and autoantibody production in lupus-prone mice, with potential therapeutic implications for SLE.

METAHICT improves metagenomic Hi-C analysis by integrating binning, reassembly, and downstream tools to recover high-quality MAGs and reduce contamination.

This study shows that the F. prausnitzii strain UT1 alters gut microbiome composition and carbohydrate metabolism in C57BL/6 mice.

This study shows that glutaminolysis supports lupus Tfh cell function, and its inhibition reduces autoantibody production and disease in lupus-prone mice.

AuPhos enhances intestinal epithelial cell mitochondrial function, reduces mucosal oxygen delivery, and corrects dysbiosis and metabolic imbalances in IBD.

The paper shows that dietary tryptophan and genetic factors shape gut microbiota, which in turn influence autoimmune activation in lupus.