Author

Jiusheng Yan

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-6633-1799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Xin Guan· 2 shared Canwei DuiD· 1 shared Kunal R. ShahiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersCell Biology

Xin Guan

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2 papers

Recent·Most cited

NAADP elicits two-pore channel currents by lifting Lsm12-mediated inhibition of PI(3,5)P2 activation

Xin Guan, Canwei Du, Kunal R. Shah, Jiusheng Yan

This study shows NAADP reverses Lsm12 inhibition of PI(3,5)P2-dependent TPC activation, enabling Ca2+ release from acidic organelles.

bioRxiv · Apr 15, 2026 · PreprintCell Biology

LRRC55 modulates BK channels to support Purkinje cell plasticity and motor coordination

Xin Guan, Jiusheng Yan

This study identifies LRRC55 as an auxiliary subunit of BK channels in Purkinje cells, showing its role in motor coordination and synaptic plasticity through BK channel modulation.

bioRxiv · Apr 1, 2026 · PreprintNeuroscience