Cancer BiologyMolecular and Cellular PediatricsPeer-reviewed
Widespread Prevalence of CD19 Exon 5-6 Skipping In Indian Pediatric B-cell Acute Lymphoblastic Leukemia Patients
Devesh Srivastava, Anurag Gupta, Nishant Verma, Ashish Misra
The paper reports that 55% of pediatric B-ALL patients have CD19 isoforms missing exons 5-6, potentially due to RC3H1 and MBNL1 dysregulation, contributing to CART therapy resistance.
2 citations