Residue-specific dominant-negative mutant of ubiquitin reveals functional selectivity as Ubp14 deubiquitinase inhibitor
Amrita Arpita Padhy, Saanya Yadav, Subhashree Sahoo…·Parul Mishra
The paper identifies a residue-specific dominant-negative ubiquitin mutant that selectively inhibits Ubp14 deubiquitinase activity, revealing functional selectivity in proteostasis regulation.