Author

Hunter Colegrove

University of WashingtonORCID 0000-0002-6660-8460Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

Alison F. FederiD· 2 shared Brendan F. KohrniD· 1 shared Charles C. ValentineiD· 1 shared Desiree A. MarshalliD· 1 shared Elizabeth K. SchmidtiD· 1 shared Eric Quentin KonnickiD· 1 shared Fang Yin LoiD· 1 shared Henry Marshall· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Alison F. FederORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 20, 2026

✦ In-depth digest

Ultra-deep duplex sequencing reveals unique features of somatic evolution in the normal tissues of a family with Li-Fraumeni syndrome

Hunter Colegrove, Marianne E. Dubard-Gault, Henry Marshall…·Rosa Ana Risques

Duplex sequencing of a Li-Fraumeni family links germline TP53 p.R181H to higher neutral-region mutagenesis and weaker blood TP53 selection, plus recurrent p.R248Q/W hits across proband tissues.

DOI 10.64898/2026.01.12.699071

humanwhole-genome sequencing

𝕏 PostBluesky

Cell BiologyPLoS Computational BiologyPeer-reviewedSep 10, 2025

Epithelial competition determines gene therapy potential to suppress Fanconi Anemia oral cancer risk

Hunter Colegrove, Raymond J. Monnat, Alison F. Feder

This paper uses a computational model to show that gene-corrected cells must have strong proliferative advantages to spread in the oral epithelium and that delivering correction to many cells reduces stochastic loss.

DOI 10.1371/journal.pcbi.1012915

humandeep learning

𝕏 PostBluesky