Eric Quentin Konnick

This paper constructs a unified transcriptional landscape of breast cancer using bulk RNA-seq data from multiple cohorts, identifying subtype and microenvironmental programs associated with therapeutic resistance.

The paper constructs a unified transcriptomic landscape of lung cancer using RNA-seq data from 1,824 tumors, identifying nine molecular clusters with distinct biological and clinical features.

Duplex sequencing of a Li-Fraumeni family links germline TP53 p.R181H to higher neutral-region mutagenesis and weaker blood TP53 selection, plus recurrent p.R248Q/W hits across proband tissues.

This paper introduces a 3D microdissection method combining CNC milling and light-sheet microscopy to study tumor evolution in complex 3D structures.

This study evaluates the impact of a 3D pathology workflow on DNA, RNA, and protein integrity, showing minimal effect on amplifiability and transcriptomic profiles.

SwabExpress is a simplified COVID-19 testing protocol that eliminates the need for transport media and nucleic acid extraction, achieving high sensitivity and specificity.