Cyrille Mathieu

This study identifies cis-aconitate as a dual-action antiviral and anti-inflammatory agent that reduces influenza mortality in mice by targeting viral polymerase and ERK/AKT/NF-κB signaling.

This study shows that NAD metabolism is critical for influenza A virus replication in an ex vivo mouse lung model, with PARP inhibition reducing viral production.

This study compares two Toscana virus strains from different genetic lineages in cell culture and mouse models, showing differences in replication efficiency and CNS dissemination.

This study shows that HTLV-1-infected T cells alter the transcriptional and functional responses of dendritic cells, leading to a tolerogenic immune environment.