Axel Thieffry

This study identifies two roles of terminal nucleotidyl transferases (TNTases) in secondary siRNA amplification in Arabidopsis, showing URT1 inhibits initiation while HESO1 and others promote siRNA formation by modifying dsRNA.

The paper investigates how nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis by analyzing mutant phenotypes and molecular mechanisms.

The paper reassesses the existence of PROMPTs and eRNAs in Arabidopsis thaliana using RNA sequencing in nuclear decay mutants, identifying exosome-sensitive transcripts and antisense RNAs.

CAGEfightR is an R/Bioconductor package for analyzing CAGE data, enabling TSS and enhancer identification, annotation, quantification, and visualization.

This study provides a comprehensive TSS map for fission yeast under various stress and media conditions using CAGE, revealing new insights into gene regulation and promoter diversity.