Simon Bressendorff

The tryptophan-binding pockets of Arabidopsis AGO1 facilitate amplified RNA interference via SGS3

The paper identifies that tryptophan-binding pockets in Arabidopsis AGO1 are essential for RDR6-dependent siRNA amplification through interactions with SGS3.

The N-coil and the globular N-terminal domain of plant ARGONAUTE1 are interaction hubs for regulatory factors

The paper identifies interaction hubs in the N-terminal domain of plant ARGONAUTE1, showing distinct regions involved in binding regulatory factors like autophagy receptors and F-box proteins.

Distinction between small RNA-bound and free ARGONAUTE via an N-terminal protein-protein interaction site

The paper identifies an N-terminal region in AGO proteins that is accessible in the RNA-free state and mediates specific degradation through interaction with ATI1.

Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis

The paper investigates how nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis by analyzing mutant phenotypes and molecular mechanisms.

The Arabidopsis autophagy cargo receptors ATI1 and ATI2 bind to ATG8 via intrinsically disordered regions and are post-translationally modified upon ATG8 interaction

This paper investigates the molecular properties of Arabidopsis autophagy cargo receptors ATI1 and ATI2, showing their intrinsically disordered regions and post-translational modifications upon ATG8 interaction.