Author

Sophie M Hurwitz

University of WashingtonORCID 0000-0002-6720-2761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Sharona E. GordoniD· 1 shared Suzanne C. HoppinsiD· 1 shared William N. ZagottaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Sharona E. GordonORCID

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1 paper

Recent·Most cited

BiophysicsThe Journal of Cell BiologyPeer-reviewedApr 2, 2026

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1.

Sophie M Hurwitz, William N. Zagotta, Sharona E. Gordon, Suzanne C. Hoppins

This study uses tmFRET to analyze GTP-coupled conformational changes in Mfn1, revealing an unexpected conformational reversal and heterogeneous transition-state ensemble.

1 citation

experimental assaycell signaling & trafficking

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