Nadja Makki

The paper identifies 92 functional regulatory variants associated with adolescent idiopathic scoliosis using massively parallel reporter assays in chondrocytes.

The paper identifies tissue-specific molecular changes in paraspinal muscle and spinal cartilage in AIS patients, linking non-coding genetic risk variants to dysregulated developmental pathways.

This study identifies AIS-associated genes and regulatory elements through RNA-seq and ChIP-seq in human and mouse tissues, revealing pathways involved in chondrogenesis and connective tissue maintenance.

This study identifies ADGRG6 as a regulator of intervertebral disc homeostasis through STAT3 signaling, showing that inhibiting STAT3 reduces disc degeneration in a mouse model.