Author

Garrett W. D. Easson

Washington University in St. LouisORCID 0000-0003-0078-6296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Simon Y. TangiD· 3 shared Remy E. WalkiD· 2 shared Sade W. ClaytoniD· 2 shared Aimy SebastianiD· 1 shared Gabriela G. LootsiD· 1 shared Jingjing ZhaoiD· 1 shared Kaitlyn S. BroziD· 1 shared Laura Mpofu· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Simon Y. TangORCID

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3 papers

Recent·Most cited

Cell BiologyExperimental Cell ResearchPeer-reviewedJul 30, 2025

Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury

Sade W. Clayton, Aimy Sebastian, Stephen P. Wilson…·Simon Y. Tang

This study uses single-cell RNA sequencing to analyze changes in cell function and maturation in the intervertebral disc after injury, identifying key cell populations and pathways involved in degeneration.

9 citationstop 2%

mousescRNA-seq

𝕏 PostBluesky

Cell BiologyOsteoarthritis and CartilagePeer-reviewedOct 18, 2024

Analysis of Infiltrating Immune Cells Following Intervertebral Disc Injury Reveals Recruitment of Gamma-Delta (????) T cells in Female Mice

Sade W. Clayton, Remy E. Walk, Laura Mpofu…·Simon Y. Tang

This study identifies sex-specific immune cell responses following intervertebral disc injury, revealing differential recruitment of gamma-delta T cells in female mice and NKT cells in males.

17 citationstop 3%

mousebulk RNA-seq

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Developmental BiologyPLoS GeneticsPeer-reviewedOct 25, 2019

Homeostasis of the intervertebral disc requires regulation of STAT3 signaling by the adhesion G-protein coupled receptor ADGRG6

Zhaoyang Liu, Garrett W. D. Easson, Jingjing Zhao…·Ryan S. Gray

This study identifies ADGRG6 as a regulator of intervertebral disc homeostasis through STAT3 signaling, showing that inhibiting STAT3 reduces disc degeneration in a mouse model.

35 citations

mouseexperimental assay

𝕏 PostBluesky