Author

Tadayoshi Karasawa

Jichi Medical UniversityORCID 0000-0002-6738-2360Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Chintogtokh BaatarjaviD· 2 shared Masafumi TakahashiiD· 2 shared Takanori KomadaiD· 2 shared Daisuke YamamuroiD· 1 shared Emi AizawaiD· 1 shared Hidetoshi AizawaiD· 1 shared Junya ItoiD· 1 shared Kiyotaka NakagawaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Chintogtokh BaatarjavORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 13, 2026

Inflammasome activation drives gasdermin-independent plasma membrane rupture by clustering ninjurin-1 in macrophages

Tadayoshi Karasawa, Hidetoshi Aizawa, Takanori Komada…·Masafumi Takahashi

This study shows inflammasome activation causes necrotic cell death in macrophages without gasdermin D or E by clustering ninjurin-1, leading to plasma membrane rupture and IL-1β release.

DOI 10.64898/2026.04.10.717393

mouseexperimental assay

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Molecular BiologybioRxivPreprintJun 15, 2022

DHCR7 as a novel regulator of ferroptosis in hepatocytes

Naoya Yamada, Tadayoshi Karasawa, Takanori Komada…·Masafumi Takahashi

This study identifies DHCR7 as a regulator of ferroptosis in hepatocytes, showing that its inhibition suppresses ferroptosis through 7-DHC accumulation and highlights its therapeutic potential for liver diseases.

8 citations

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