Extracellular Vesicle-delivered Bone Morphogenetic Proteins: A novel paracrine mechanism during embryonic development
Thomas Draebing, Jana Heigwer, Lonny Juergensen, Hugo Albert Katus, David Hassel
The paper identifies extracellular vesicles (EVs) as a mechanism for transporting BMP2/4 during zebrafish embryonic development, leading to dorsalization phenotypes when EV secretion is inhibited.
bioRxiv · May 14, 2018 · PreprintDevelopmental Biology