BiochemistrybioRxivPreprint
Designed Minibinders Rewire Receptor Signaling to Enable Functional Human Myogenic Reprogramming
Riya Keshri, Zachary Foreman, Philip Barrett…·Hannele Ruohola‐Baker
This paper demonstrates that AI-designed receptor modulators can drive efficient human fibroblast-to-muscle transdifferentiation by rewiring extracellular signaling.
DOI 10.64898/2026.04.26.720818