Author

Halewijn van den Bossche

Delft University of TechnologyORCID 0000-0002-6801-5167Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana Rita CostaiD· 2 shared Aswin MuralidharaniD· 2 shared Daan F. van den BergiD· 2 shared Stan J. J. BrounsiD· 2 shared Adja Damba Zoumaro-DjayooniD· 1 shared Alicia Rodríguez-MolinaiD· 1 shared Bruno E. CorreiaiD· 1 shared Desi Fierlier· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

Ana Rita CostaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular basis for anti-jumbo phage immunity by AVAST Type 5

Aswin Muralidharan, Ana Rita Costa, Desi Fierlier, Daan F. van den Berg, Halewijn van den Bossche, Adja Damba Zoumaro-Djayoon, Alicia Rodríguez-Molina, Martin Pabst, Martin Pačesa, Bruno E. Correia, Stan J. J. Brouns

This study identifies Avs5 systems as a conserved bacterial defense against jumbo phages, revealing their mechanism of recognizing and disrupting phage infection.

Molecular Cell · Feb 1, 2026Peer-reviewedMicrobiology

Discovery of phage defense systems through component modularity networks

Daan F. van den Berg, Ana Rita Costa, Jelger Q. Esser, Aswin Muralidharan, Halewijn van den Bossche, Stan J. J. Brouns

The paper identifies phage defense systems by analyzing modular gene clusters, validating three new systems through experimental testing.

bioRxiv · Sep 30, 2025 · PreprintMicrobiology